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pharmacogenomics
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Reseña del libro "pharmacogenomics"
expert researchers and physician/clinicians describe in detail the newest and most commonly used technologies today in this rapidly advancing field. the authors provide readily reproducible methods for assessing the functional consequences of a certain polymorphism, evaluate the variety of genotyping platforms currently available, and discuss the management of pharmacogenomic information. highlights include techniques for making a snapshot of the allele-specific variation in human gene expression, genome wide analysis of allele-specific expression using oligo microarrays, in vivo assays with haplochip, snp genotyping in dna pools, and pharmgkb, the pharmacogenetics and pharmacogenomics knowledge base. the methodologies for genotyping include denaturing high-performance liquid chromarography, pyrosequencing, kinetic-fluorescence detection, mass spectrometry, and taqman assay for insertion/deletions.
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